Tesamorelin 5mg

What is Tesamorelin?

Tesamorelin is a synthetic analog of GHRH (growth hormone releasing hormone) composed of the full 44-amino-acid GHRH sequence with a trans-3-hexenoic acid modification that increases its stability and potency. It is FDA-approved under the brand name Egrifta for the treatment of HIV-associated lipodystrophy (abnormal fat distribution), making it one of the few GHRH analogs with a specific FDA approval. Its clinical track record sets it apart from many other peptides in this class.

How It Works

Like sermorelin, tesamorelin stimulates the pituitary gland to release growth hormone naturally. Its modified structure makes it more resistant to enzymatic degradation, resulting in a longer duration of action and more robust pituitary stimulation compared to shorter GHRH analogs. The result is a more sustained increase in growth hormone output, leading to downstream effects on IGF-1 levels, fat metabolism, and body composition.

Key Benefits

In FDA-approved clinical use, tesamorelin has demonstrated significant reductions in visceral abdominal fat — the metabolically active fat surrounding internal organs that is associated with cardiovascular and metabolic risk. Beyond its approved indication, it is studied and used in integrative medicine for body composition optimization, improved exercise capacity, and metabolic support. Research suggests it is more potent than sermorelin in stimulating growth hormone release in certain clinical comparisons.

What to Expect

Tesamorelin is administered via daily subcutaneous injection. Clinical trials showed measurable reductions in visceral fat over 26 weeks of use. Body composition improvements — including leaner abdominal profile and improved muscle-to-fat ratio — are typically observable over a 3–6 month course. As with all GH-stimulating therapies, individual results depend on baseline hormone levels, diet, activity, and adherence to the protocol.

Quality & Sourcing

Every tesamorelin formulation from Greenstone Peptides is compounded in the USA by licensed pharmacy partners under USP 797 sterile standards. Each batch is third-party tested for potency, sterility, and endotoxin.