NAD+ Nasal Spray 300mg/mL

What is NAD+?

NAD+ stands for Nicotinamide Adenine Dinucleotide. It is a coenzyme found in every living cell and is essential to hundreds of metabolic processes. Without NAD+, cells cannot produce energy, repair DNA, or maintain normal function. The challenge is that NAD+ levels decline significantly with age — studies suggest levels drop by approximately 50% between the ages of 40 and 60 — contributing to the cellular slowdown associated with aging.

How It Works

NAD+ serves as a critical electron carrier in cellular respiration, enabling mitochondria to convert nutrients into ATP (cellular energy). It is also required by sirtuins — proteins associated with longevity and cellular stress responses — and by PARP enzymes involved in DNA repair. Supplementing NAD+ aims to restore depleted cellular levels, giving cells the substrate they need to function at a higher capacity.

Key Benefits

Research links NAD+ supplementation to improved energy levels, mental clarity, and cellular metabolism. Studies in aging models have shown associations between higher NAD+ levels and improved mitochondrial function, reduced inflammation, and better metabolic health markers. It is available in injectable form for direct systemic delivery and as a nasal spray for rapid intranasal absorption — both bypassing digestive breakdown for improved bioavailability compared to oral supplements.

What to Expect

Injectable NAD+ is often described as producing a notable boost in energy and mental focus, sometimes within hours of administration. The nasal spray format offers a more convenient daily option with steady systemic absorption. Many patients use NAD+ as part of a broader longevity or metabolic optimization protocol alongside peptides like MOTS-c or sermorelin. Protocols vary widely — dosing and frequency should be determined with a prescribing physician.

Quality & Sourcing

Every NAD+ formulation from Greenstone Peptides is compounded in the USA by licensed pharmacy partners under USP 797 sterile standards. Each batch is third-party tested for potency, sterility, and endotoxin.